Safe use of livers from donors with positive hepatitis B core antibody
نویسندگان
چکیده
منابع مشابه
Liver transplantation in hepatitis B core-negative recipients using livers from hepatitis B core-positive donors: a 13-year experience.
The use of livers from hepatitis B surface antigen-negative (HBsAg- )/hepatitis B core antibody-positive (HBcAb+ ) donors in liver transplantation (LT) for HBsAg(-) /HBcAb- recipients is still controversial because of a lack of standard antiviral prophylaxis and long-term follow-up. We present our 13-year experience with the use of HBcAb+ donor livers in HBcAb- recipients. Patients received pro...
متن کاملUse of hepatitis B core antibody-positive donors in orthotopic liver transplantation.
HYPOTHESIS Hepatic allografts from donors positive for antibody to hepatitis B core antigen (anti-HBc) frequently transmit hepatitis B virus (HBV) infection to recipients. Therefore, most transplantation centers will not use these organs for orthotopic liver transplantation (OLT). Although it is expensive and not always efficacious, hepatitis B immune globulin (HBIG) has been used routinely for...
متن کاملUse of liver grafts from anti-hepatitis B core-positive donors: a multicenter study in Argentina.
Liver transplantation success is limited by the availability of donors. To overcome this limitation, anti-core-positive donors are increasingly being accepted, but underutilization of this resource still occurs. We performed the current study to determine the prevalence of anti-core-positive donors in our region and to describe the management of these donors and their recipients. Between Januar...
متن کاملPrevention of de novo hepatitis B virus infection in living donor liver transplantation using hepatitis B core antibody positive donors.
Exclusion of liver grafts from hepatitis B core antibody (anti-HBc) positive donors to prevent de novo hepatitis B virus (HBV) infection after liver transplantation is not feasible in areas highly endemic for HBV virus like Taiwan, where approximately 80% of adults are anti-HBc(+). The efficacy of lamivudine monotherapy to prevent de novo HBV infection after living donor liver transplantation (...
متن کاملAre we ready for marginal hepatitis B core antibody-positive living liver donors?
Adult-to-adult living donor liver transplantation (LDLT) is being performed in the United States with increasing frequency because of the severe shortage of cadaveric donor organs.1,2 For example, 42 of 89 Organ Procurement and Transplantation Network– certified liver transplant programs (47%) reported having performed at least one adult-to-adult LDLT in 2000, and 355 adult-to-adult LDLTs were ...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2002
ISSN: 1527-6465
DOI: 10.1053/jlts.2002.33451